Analgesics and antipyretics

At some point in our lives, we have likely experienced pain or fever. These symptoms are common in several diseases and conditions, and at these times, analgesics and antipyretics become our allies to relieve discomfort. 1 Let's analyze together how these medications work and when it is appropriate to use them, to understand what is the appropriate use to give them.

Differences between analgesics and antipyretics

Analgesics are medications designed to relieve pain, mainly muscle, head, or joint pain, while antipyretics, also called antipyretics or fever reducers, are intended to reduce fever, having the ability to restore body temperature to normal levels. after having experienced an increase in it. 2 These drugs act on our body in various ways to mitigate uncomfortable symptoms and help us feel better.

Mechanisms of action of analgesics and antipyretics:

Pain relievers work by blocking the transmission of pain signals from the nerves to the brain. 3 Some pain relievers, such as nonsteroidal anti-inflammatory drugs (NSAIDs), work by inhibiting an enzyme called cyclooxygenase (COX). This reduces the production of prostaglandins, which are chemicals that cause inflammation and pain. 4 Other pain relievers, such as opioids, work by binding to opioid receptors in the brain and spinal cord, decreasing the perception of pain. 5

On the other hand, antipyretics act on the temperature-regulating center in the brain to reduce fever. 6 One of the most common antipyretics is paracetamol, which has analgesic and antipyretic effects. Paracetamol blocks the production of prostaglandins in the brain, which helps reduce fever and associated discomfort. 7

When to use pain relievers and antipyretics

Proper use of pain relievers and antipyretics involves understanding when it is appropriate to use them and when you should seek medical attention. These medications are useful for relieving mild to moderate pain, such as headaches, muscle aches, menstrual pain, and pain associated with common colds. They are also used to reduce fever in cases of viral or bacterial infections. 8

However, it is important to note that these drugs only treat the symptoms and not the underlying cause of the pain or fever. 9 If symptoms persist or worsen, medical advice should be sought to determine the cause and receive appropriate treatment.

Tips for the correct taking of analgesics and antipyretics

Although pain relievers and antipyretics are widely used over-the-counter medications, it is essential to use them with caution and follow recommended dosage instructions. Some important considerations include:

• Do not exceed the recommended dose: Taking more than the indicated dose will not increase the effectiveness of the medication and may be harmful to your health. 10
• Respect the dosage interval: It is important to follow the recommended time between doses to avoid overdose or excessive accumulation of the medication in the body. eleven
• Consult a health professional: It is always advisable to speak with a doctor or pharmacist before starting any treatment with analgesics or antipyretics, especially if you have a pre-existing medical condition, such as liver, kidney, or heart disease.
• Avoid combining medications: If you are taking other medications or supplements, it is essential to check the compatibility and possible interactions with analgesics and antipyretics. Some combinations can be dangerous and affect the effectiveness of the medications. 12
• Responsible use in children and pregnant women: In the case of children, it is crucial to follow the specific recommendations for their age and weight. As for pregnant women, you should always consult a doctor before taking any medication, as some pain relievers and antipyretics may not be safe during pregnancy. 13
• Side effects and allergies: It is possible to experience side effects such as stomach upset, nausea, dizziness, or drowsiness when taking pain relievers and antipyretics. In rare cases, some people may develop allergic reactions. If adverse effects occur, it is important to discontinue use and seek medical attention. 14
• Proper storage: Medications should be kept in a cool, dry place, out of the reach of children. Expired medications should not be used, as they may be less effective or potentially dangerous. fifteen

Analgesics and antipyretics are important tools to relieve pain and reduce fever, giving us temporary relief in various symptoms. Understanding how these medications work and when it is appropriate to use them allows us to make informed decisions to improve our health. 

Eurofarma has products in the OTC line for every need; ACF 500 Paracetamol, with its analgesic power, relieves any type of occasional pain quickly and effectively. ACF C, ACF Grip, and ACF Plus, due to their anti-flu and decongestant characteristics, act quickly, relieving the symptoms of flu and colds. ACF is three letters that guarantee well-being and Quality.